The Library of Integrated Network-Based Cellular Signatures (LINCS) is an NIH Common Fund program with the goal of generating a large-scale and comprehensive catalogue of perturbation-response signatures by utilizing a diverse collection of: Perturbations (e.g. chemical, genetic, disease state) Model Systems (e.g. cell lines, differentiated cells, embryonic stem cells) and Sssay Types (e.g. gene expression, protein expression,...
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Ontology sounds a lot like a medical specialty—but it’s not related to Oncology, Otolaryngology, or Ophthalmology—except that researchers organizing Big Data in Biomedicine into different ‘ontologies’ or categories could help expedite new drug targets and discoveries in these specialties, and others, in the future. The University of Miami Miller School of Medicine is joining a partnership to combine advances in ontologies, templates,...
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If you build it, the data will not only come, it will be standardized, accessible, and reusable by researchers around the world. With this in mind, the National Institutes of Health (NIH) is creating its Data Commons initiative, and recently invited University of Miami investigators to contribute their expertise. "There is a big effort at the NIH now to bring biomedical research into the data science era. Data science including...
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It’s part genomics*, part big data, and all about driving discoveries that could someday translate to new treatments for cancer, neurological diseases, addiction, and many other conditions, said Stephan Schürer, Ph.D., CCS Drug Discovery program director, and associate professor of molecular and cellular pharmacology at the UM Miller School of Medicine. The NIH’s "Illuminating the Druggable Genome" (IDG) initiative is expected to...
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Stephan Schürer, Ph.D., Associate Professor of Molecular and Cellular Pharmacology at the Miller School and Chemoinformatics Program Leader at CCS leads the team of University of Miami researchers funded through NIH to create a Data Coordination and Integration Center for the Library of Integrated Network-based Cellular Signatures (LINCS) program. Read the NIH press release. More on BD2K....
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