Office: Room 6112A, Rosenstiel Medical Science Building (RMSB), 1600 NW 10th Avenue, Miami, FL 33136
Afoma C. Umeano is an MD/PhD at the University of Miami Miller School of Medicine. Her PhD is focused on medicinal and computational chemistry applications in Molecular and Cellular Pharmacology. Her projects are based on the rational design and synthesis of small libraries targeting epigenetic modulators and kinases for the treatment of various cancers. Also, she employs the use of computational chemistry and various analytics towards the discovery of protein targets for known active compounds. This work is partially funded by the NIH common-fund project “Illuminating the Druggable Genome” and the “Library of Integrated Network of Cell-Based Signatures (LINCS), where she lends her knowledge of chemistry towards standardization of pipelines for the LINCS data portal.
Her research interests include natural product synthesis, fragment-based drug design, drug design for oncological diseases, target-based drug design, and diversity-oriented medicinal chemistry. Her clinical interests include pediatric oncology, immunology, and pediatric surgery.