The Computational Biology & Bioinformatics (CBB) Program conducts research and offers services and training in the management and analysis of biological and biomedical data.
The CBB faculty and staff are a diverse group of interdisciplinary specialists with research interests that span the life sciences, and Computational Biology & Bioinformatics expertise areas in building infrastructure, developing algorithms, and designing and implementing analytical approaches. The data CBB handles ranges from species ecology through to genomic medicine. Particular focus areas are illustrated on our Research page.
The CBB Program brings computer scientists and engineers together with clinicians and medical research scientists to develop the methods and tools needed for the analysis of complex high-dimensional data sets.
Office: Room 600N, Gables One Tower
Dr. Nicholas Tsinoremas holds faculty appointments at the Miller School of Medicine and the College of Arts and Sciences at the University of Miami. He is the Founding Director for the University of Miami Center for Computational Science.
Dr. Tsinoremas is an international leader in computational genomics and bioinformatics, and brings over 25 years of academic and industrial experience to the University of Miami. He received his B.A. in Chemistry from the University of Athens, Greece, and his Ph.D. in Molecular Biology from the University of Leeds, UK. Before joining the University of Miami, he served as Senior Director of Informatics at The Scripps Research Institute-Florida. There, he recruited and managed the Informatics and IT groups for the newly formed Scripps Florida.
As Director of Computational Genomics and Genomic Discovery at Rosetta/Merck where he directed the project that combined informatics and computational approaches with gene expression profiling and genetics to discover, prioritize, and define drug target genes. Prior to working for Merck/Rosetta, Tsinoremas was the Vice-President of Genomics at DoubleTwist Inc., where he determined the scientific direction of DoubleTwist’s bioinformatics applications and databases.
Office: 1301 Memorial Drive, Suite 73
Office: Clinical Research Building, Room R-669
Office: UM Medical Campus, Room 1205J, Dominion Tower
Office: 1095 NW 14th Street
Office: Room 1301, Cox Science Center
Phone: +33 (0)6 29 22 62 87
Alessandra Cervino is a scientific director with 20 years of experience in the discovery and development of genetic and genomic biomarkers, with particular strength in “In Silico” discovery strategies. Recently, she was the Head of Metagenomic Discovery at Enterome Bioscience in France.
Before joining Enterome, Alessandra was VP R&D and Biostatistics at TCLand expression, a personalized medicine company developing companion diagnostics and biomarkers for immune disorders and transplantation. She was previously Head of Statistical Sciences and Assistant Professor at Scripps Florida, where she conducted the first genome-wide study of lupus and developed an innovative workflow that combines genotypic and transcriptomic data to identify novel genes. She was the first group leader in statistical genetics at Rosetta Inpharmatics/Merck in the USA, where she played a pioneering role in translating genetic research programs into new drug targets and pharmacogenomic programs.
Prof. Cervino holds a PhD in Clinical Medicine from the University of Oxford, UK, an MSc in Biometry from the University of Reading, UK and a Mathematics degree from the Free University in Brussels, Belgium. She is the inventor of four patents. She also holds an honorary senior lectureship from Kings College London.
Office: Clinical Research Building, CRB R-669
Dr. Chen received his Doctoral degree in Statistics from the North Carolina State University. His research is focused on statistical genomics for cancer research, especially developing and applying innovative statistical and bioinformatics methodology to facilitate translational genomic research from bench to clinic. Dr. Chen is the Principle Investigator of a NCI R01 grant “Integrative prediction models for metastasis risk in colon cancer” which collects data on mRNA expression, somatic mutations, and clinical information to develop clinical-genomic risk prediction models and subtypes for colon cancer patients. Dr. Chen is also a major contributor for identifying six triple-negative breast cancer (TNBC) subtypes and corresponding gene signatures. He is the developer of the web-based software “TNBCtype”, which has been widely used by breast cancer research community.
Office: 257A Cox Science Center
Office: Room 442, Center for Collaborative Research, NSU Institute for Neuro-Immune Medicine
Travis Craddock, PhD is an assistant professor of Psychology, Computer Science and Medicine applying systems biology and biophysics methods towards the purpose of identifying novel treatments for complex chronic illness involving neuroinflammation. His postdoctoral work was conducted under the supervision of Gordon Broderick, PhD, in the Broderick Laboratory for Clinical Systems Biology in the Department of Medicine, Faculty of Medicine and Dentistry at the University of Alberta. His work with Gordon Broderick, PhD, focused on using a theory driven systems biology approach to investigate neuroendocrine-immune interaction dynamics in neuroinflammation and its relation complex diseases such as Gulf War Illness, and chronic fatigue syndrome. This work was funded by the US Department of Defense.
He received his BSc in co-op physics from the University of Guelph and went on to finish a MSc and PhD in the field of biophysics at the University of Alberta under the supervision of Jack Tuszynski, PhD. His graduate research activities focused on subneural biomolecular information processing, and nanoscale neuroscience descriptions of memory, consciousness and cognitive dysfunction in neurodegenerative disorders such as Alzheimer’s disease.
More on nova.edu/nim
Office: BMC – Biomaterials Science Center, University of Basel, Gewerbestrasse 14, 4123 Allschwil, Switzerland
My name is Marco Dominietto, I’m a medical physicist with a doctoral degree in Biomedical Engineering.
My main research interests are focused on the modelling of physiological processes of tumor growth, medical imaging integration, small animal experiments, personalized and precision medicine.
As medical physicist, I spent six years in diagnostic imaging, nuclear medicine and radiotherapy departments at the University Hospital of Novara, Italy. During this time, I participated to several projects based on texture analysis, pattern recognition and image co-registration with the aim to improve the radiation dose delivery in oncological patients treated with radiation therapy.
Following these topics, I moved to Geneva at CERN (TERA Foundation) for a project related to the development of a 3D dose calculating system for proton pencil beam radiotherapy.
As a consequence, I decided to deal more with basic research, which led me to start a PhD at ETH and University of Zurich. The PhD project and the first PostDoctoral fellowship, were focused on developing multimodality imaging approaches to study tumor angiogenesis and its fractal physiology both in small animals and human beings.
I’m currently employed at the University of Basel following two main areas of interest: medical imaging integration in a context of complex network approach and the development of artificial muscles based on active polymers.
Aside the scientific activity, I am responsible for the organization of the PhD program in Biomedical Engineering at the University of Basel.
Office: 1400 NW 10th Avenue, Suite 916A
Office: McArthur Engineering Building, Room 206
Professor Weiyong Gu’s research focuses on:
- Tissue Biomechanics
- Transport Phenomena
- Continuum Mixture Theory
- Computational Biomechanics
- Mechanobiology of Intervertebral Disc
- Bioreactor Technology
CCS Member Since: October 2010
Office: Clinical Research Building, Room 1058
Office: Sieron Building, Room 308C
Office: Rosenstiel School of Marine and Atmospheric Science
Office: McArthur Engineering Building, Room 279
Office: Istituto Toscano Tumori (CRL-ITT)Pisa, Italy
Office: Ungar Building, Room 437
Office: Room 6113, Rosenstiel Medical Sciences Building
Office: Room 403, Ungar Building