Publications

2013

  • Sarntivijai, S.; Lin, Y.; Xiang, Z.; Meehan, T.F.; Diehl, A.D.; Vempati, U.D.; Schürer, S.C.; Pang, C.; Malone, J.; Parkinson, H.; Liu, Y.; Takatsuki, T.; Saijo, K.; Masuya, H.; Nakamura, Y.; Brush, M.; Haendel, M.A.; Zheng, J.; Stoeckert, C.J.; Peters, B.; Mungall, C.J.; Carey, T.E.; States, D.J.; Athey, B.D.; He, Y. “CLO: The Cell Line Ontology” J Biomed Semantics, 2013, accepted for publication.
  • Przydzial, M.J.; Bhhatarai, B.; Koleti, A.; Vempati, U.; Schürer, S.C. “GPCR ontology: development and application of a G protein-coupled receptor pharmacology knowledge framework” Bioinformatics, 2013, in press, doi:10.1093/bioinformatics/btt565.
  • Satsu, H.; Schaeffer, M.T.; Guerrero, M.; Saldana, A.; Eberhart, C.; Hodder, P.; Cayanan, C.; Schürer, S.; Bhhatarai, B.; Roberts, E.; Rosen, H.; Brown, S.J. “A sphingosine 1-phosphate receptor 2 selective allosteric agonist” Bioorg. Med. Chem. 2013, 5373-82, doi:10.1016/j.bmc.2013.06.012, http://www.sciencedirect.com/science/article/pii/S0968089613005439.
  • Bibian, M.; Rahaim, R.J.; Choi, J.Y.; Noguchi, Y.; Schürer, S.; Chen, W.; Nakanishi, S.; Licht, K.; Rosenberg, L.H.; Li, L.; Feng, Y.; Cameron, M.D.; Duckett, D.R.; Cleveland, L.L.; Roush, W.R. “Development of highly selective casein kinase 1δ/1ε (CK1δ/ε) inhibitors with potent antiproliferative properties” Bioorg. Med. Chem. Lett. 2013, 4374-80, doi:10.1016/j.bmcl.2013.05.075, http://www.sciencedirect.com/science/article/pii/S0960894X13006707.
  • Al-Ali, H.; Schürer, S.C.; Lemmon, V.P.; Bixby, J.L. “Chemical Interrogation of the Neuronal Kinome Using a Primary Cell-Based Screening Assay.” ACS Chem Biol, 2013, doi:10.1021/cb300584e, http://pubs.acs.org/doi/abs/10.1021/cb300584e.
  • Wolfe, L.M.; Veeraraghavan, U.; Idicula-Thomas, S.; Schurer, S.; Wennerberg, K.; Reynolds, R.; Besra, G.S.; Dobos, K.M. “A Chemical Proteomics Approach to Profiling the ATP-Binding Proteome of Mycobacterium tuberculosis.” Mol Cell Proteomics, 2013, doi:10.1074/mcp.M112.025635; http://www.mcponline.org/content/early/2013/03/05/mcp.M112.025635.long.
  • Schürer, S.C., Muskal, S.M. “Kinome-wide Activity Modeling from Diverse Public High-Quality Data Sets” J Chem Inf Model, 2013, doi:10.1021/ci300403k; http://pubs.acs.org/doi/abs/10.1021/ci300403k.

2012

  • Vidović, D.; Muskal, S.M.; Schürer S.C. “Novel Kinase Inhibitors by Reshuffling Ligand Functionalities Across the Human Kinome” J Chem Inf Model, 2012, 3107–3115, doi:10.1021/ci3003842; http://pubs.acs.org/doi/abs/10.1021/ci3003842.
  •  Jo, E.; Bhhatarai, B.; Repetto, E.; Guerrero, M.; Riley, S.; Brown, S.J.; Kohno, Y.; Roberts, E.; Schürer, S.C.; Rosen, H. “Novel Selective Allosteric and Bitopic Ligands for the S1P(3) Receptor” ACS Chem Biol 2012, doi:10.1021/cb300392z; http://pubs.acs.org/doi/abs/10.1021/cb300392z.
  •  Vempati, U.D.; Przydzial, M.J.; Chung, C.; Abeyruwan, S.; Mir, A.; Sakurai, K.; Visser, U.; Lemmon, V.P.; Schürer, S.C. “Formalization, Annotation and Analysis of Diverse Drug and Probe Screening Assay Datasets using the BioAssay Ontology (BAO).” PLoS One, 2012, doi:10.1371/journal.pone.0049198.
  • Wang, L.; Perera, B.G.K.; Hari, S.B.; Bhhatarai, B.; Backes, B.J.; Seeliger, M.A.; Schürer, S.C.; Oakes, S.A.; Papa, F.R.; Maly, D.J. “Divergent allosteric control of the IRE1α endoribonuclease using kinase inhibitors”, Nature Chem Biol 2012, doi:10.1038/nchembio.1094;http://www.nature.com/nchembio/journal/vaop/ncurrent/full/nchembio.1094.html
  •  Hanson, M.A.; Roth, C.B.; Jo, E.; Griffith, M.T.; Scott, F.L.; Reinhart, G.; Desale, H.; Clemons, B.; Cahalan, S.M.; Schuerer, S.C.; Sanna, M.G.; Han,G.W.; Kuhn, P.;Rosen, H.; Stevens, R.C “Crystal Structure of a Lipid G protein-Coupled Receptor”, Science 2012, 335, 851-5, doi:10.1126/science.1215904 http://www.sciencemag.org/content/335/6070/851.short
  •  Ganesan, L.; Vidovic, D.; Schürer, S.C.; Buchwald, P. “Exploratory computational assessment of possible binding modes for small molecule inhibitors of the CD40-CD154 co-stimulatory interaction” Pharmazie 2012, 67, 1-6, doi: 10.1691/ph.2012.1696.