Talk to us about your ideas while you are writing the grant. We can help you incorporate the cost of appropriate computational support, including appropriate software licenses and analytical personnel. The Computational Biology and Bioinformatics Program (CBBP) uses its established service center for non-collaborative projects, but prefers to collaborate with researchers on grant proposals.
The CBBG Project Intake Form provides an outline of the required information for collaborations. To request a consultation, please provide all the details as outlined and email the team at email@example.com.
The Computational Biology and Bioinformatics Group (CBBG) conducts high quality bioinformatics and statistical genetics analysis of biological and biomedical data. Our interdisciplinary team provides support services and solutions for basic science and clinical and translational research for both within and outside the University of Miami. We have expertise in building infrastructure, developing algorithms, and designing and implementing analytical approaches. We bring computer scientists and engineers together with clinicians and medical research scientists to develop the methods and tools needed for the analysis of complex, high-dimensional data sets. We offer support in study design, various “-omics” data analysis, grant and manuscript preparation, and responding to reviewers.
All the services can be provided provided on a collaborative research basis or using a fee-for-service mechanism.
1. Research Collaboration:
The CBBG provides bioinformatics support to investigators, who include a CBBG member as a co-investigator or key personnel in the grant application. Bioinformatics personnel percentage time on a grant should be representative of the actual effort required to meet deliverables and is agreed with CBBG upon grant submission. In addition, investigators should discuss and cover hardware and computational costs according to the data volume and estimated data processing time.
CBBG also provides grant preparation support including in-depth data management and preliminary data analysis. In this process, if the prospective grant is going to cover effort for a CBBG member, the first 20 hours of bioinformatics analysis are free. Any effort exceeding this should be covered on a fee-for-service basis.
2. Service Center – Fee for Service
- Alternatively, the CBBG also offers a fixed cost option for standard bioinformatics analysis with predictable effort. This includes, but is not limited to, microarray analysis, differential gene expression with RNA-seq, next-generation sequencing data alignment, and genome or transcript assembly.
- For custom solution developments with open-ended scientific questions, where it is difficult to estimate the associated time, the CBBG provides a fee-for serviceoption billed on an hourly basis.
Ultimately, the CBBG will work with the investigator to find a funding model that works best for the project at hand. Payment arrangements should be made before any services are performed, with full payment due upon completion of work. If the investigator decides to terminate the project or interrupt the collaboration before completion, hourly rates will apply. The costs will be based on actual time and resources spent on a specific project.
Project Timelines and Deadlines
The CBBG encourages principal investigators to inform the CBBG, in advance, of any deadlines for abstracts, reports, meetings and grant applications.
To better assist you, please contact the CBBG at least 6 weeks prior to the submission deadline on any grant, and earlier if the study design has yet to be fully developed. Last-minute requests may not always be accommodated due to limited resources and time constraints of other projects.
Acknowledgement and/or Co-Authorship
It is important to agree on criteria for authorship early in the collaboration. Co-authorship is requested when CBBG personnel have made a significant contribution to the research in the form of consultation, experimental design, data analysis or other material assistance, regardless of the funding mechanism. Co-authorship implies that the CBBG can defend the methodology and results of the analysis, assist in writing the methods and possibly other parts of the manuscript, and respond to reviewers comments on the bioinformatics aspects of the paper. The investigator is expected to give the CBBG an opportunity to review and edit appropriate sections of the manuscript at least one week before submission. In cases where the bioinformatician did not provide significant intellectual input (e.g. advise on experiment design or preferable methods during a meeting) acknowledgement in the manuscript is sufficient.
All data not exceeding 200 Gb will be held in the Center of Computational Science’s storage for the duration of active analysis. Thereafter, data will be subject to deletion. It is the responsibility of the investigator to ensure that a copy of the data is preserved for future analysis. Data exceeding 200 Gb will require purchase of additional storage. All costs related for additional storage and data maintenance need to be discussed and covered before the project starts.
Human Subjects Research and IRB Approval
It is the Principal investigator’s responsibility to de-identify the data and to obtain IRB approval for any project handled by CBBG, including adding amendments for CBBG personnel when applicable. IRB information may be requested before the project can proceed.